Extracorporeal shock wave therapy (ESWT) is a valuable and reliable treatment modality for musculoskeletal disorder. Even though the mechanism is still unknown, the proposed mechanisms of action for ESWT include promoting neovascularization at the tendon-bone junction, stimulating proliferation of tenocytes and osteoprogenitor differentiation, increasing leukocyte infiltration, and amplifying growth factor and protein synthesis to stimulate collagen synthesis and tissue remodeling. According to previous study, ESWT produces many beneficial effects, such as pain relief, vascularization, protein biosynthesis, cell proliferation, neuro and chondroprotection, and destruction of calcium deposits in musculoskeletal structures. In this section of speech, the application of ESWT in wrist disorder will be introduced. Some cases will also be discussed in this section. The purpose of this section is to provide current evidence on the physical and biological principles, mechanism of action and clinical efficacy of ESWT on the wrist disorders.